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SS-31
Mitochondria-targeted tetrapeptide studied for cardiolipin interactions.
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SS-31
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SS-31 (elamipretide) is an aromatic-cationic tetrapeptide studied for its interaction with cardiolipin-rich mitochondrial membranes. Mechanistic research focuses on membrane electrostatics, cytochrome-c/cardiolipin chemistry, and mitochondrial bioenergetics.
Research Literature
Published Studies
Reference literature on this compound class, provided for research context only — not a claim of safety, efficacy, or suitability for human use.
SS-31 targets mitochondrial cardiolipin and cytochrome c ↗
Birk AV, Chao WM, Bracken C, et al. Br J Pharmacol. 2014.
Biochemical and mitochondrial-model study examining SS-31 binding to cardiolipin and its effects on cytochrome-c electron transfer, respiration, and ATP synthesis.
SS-31 binds lipid bilayers and modulates surface electrostatics ↗
Mitchell W, Ng EA, Tamucci JD, et al. J Biol Chem. 2020.
Biophysical and computational study characterizing how SS-31 partitions into model and mitochondrial membrane interfaces and changes bilayer surface electrostatics.
Handling Guidance
Storage & Handling
- Unopened (Lyophilized)
- Store refrigerated (2–8°C) and protected from light until laboratory preparation.
- After Laboratory Preparation
- Keep refrigerated and avoid repeated freeze-thaw cycles per your lab's own protocol.
- Laboratory Solvent
- Select solvent and concentration only under a validated institutional protocol appropriate to the assay.
General guidance only. Follow your institution's SOP. These materials are not for human or veterinary administration.
Common Questions
FAQ
Mitochondria-targeted tetrapeptide studied for cardiolipin interactions.
Supplied as a lyophilized (freeze-dried) laboratory research material. Solvent selection, concentration, and handling must follow a validated laboratory protocol. Not for human or veterinary administration.
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See Storage & Handling above and follow your institution's validated SOP for preparation, storage, and disposal.
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Research Use Only
Buyer Acknowledgement
Products are intended strictly for laboratory research purposes only. They are not intended for human consumption, veterinary use, medical use, household use, or to diagnose, treat, cure, or prevent any disease.
