Dihexa

Angiotensin IV-derived compound studied for synaptogenesis pathway research.

Neurochemical Research

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Dihexa

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Dihexa (PNB-0408) is a small peptide derived from angiotensin IV research, engineered as a metabolically stable analog with agonist activity at the hepatocyte growth factor (HGF)/c-Met receptor system, studied in preclinical models for its reported effects on synapse formation.

Research Literature

Published Studies

Reference literature on this compound class, provided for research context only — not a claim of safety, efficacy, or suitability for human use.

Metabolically stabilized angiotensin IV analogs as procognitive research compounds ↗

McCoy AT, Benoist CC, Wright JW, et al. J Pharmacol Exp Ther. 2013.

Preclinical study describing the development of Dihexa from the angiotensin IV/HGF research program and its reported synaptogenic activity in rodent models.

Handling Guidance

Storage & Handling

Unopened (Lyophilized): Store refrigerated (2–8°C) and protected from light until laboratory preparation.
After Laboratory Preparation: Keep refrigerated and avoid repeated freeze-thaw cycles per your lab's own protocol.
Laboratory Solvent: Select solvent and concentration only under a validated institutional protocol appropriate to the assay.

General guidance only. Follow your institution's SOP. These materials are not for human or veterinary administration.

Common Questions

FAQ

Angiotensin IV-derived compound studied for synaptogenesis pathway research.

Supplied as a lyophilized (freeze-dried) laboratory research material. Solvent selection, concentration, and handling must follow a validated laboratory protocol. Not for human or veterinary administration.

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A COA is available for qualifying batches — view it above on this page, or browse the full archive on the COAs page.

See Storage & Handling above and follow your institution's validated SOP for preparation, storage, and disposal.

No. Every product on this site is sold strictly for laboratory research use — not for human or veterinary consumption.

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Research Use Only

Buyer Acknowledgement

Products are intended strictly for laboratory research purposes only. They are not intended for human consumption, veterinary use, medical use, household use, or to diagnose, treat, cure, or prevent any disease.

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